Klinefelter's Syndrome Accompanied by Diabetes Mellitus and Diabetes Insipidus

Kazuo ISOBE; Toyoo NIWA; Mitsuru OHKUBO; Midori OHBA; Masahiko SHIKANO; Yukio WATANABE

doi:10.2169/internalmedicine.31.917

Kazuo ISOBE, Toyoo NIWA, Mitsuru OHKUBO, Midori OHBA, Masahiko SHIKANO, Yukio WATANABE

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Keywords: hyperosmolar diabetic coma, metabolic acidosis, ketosis, desmopressin

JOURNAL FREE ACCESS

1992 Volume 31 Issue 7 Pages 917-921

DOI https://doi.org/10.2169/internalmedicine.31.917

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Abstract

The first case of Klinefelter's syndrome accompanied by diabetes insipidus and diabetes mellitus is reported. A 41-year-old man admitted for hyperosmolar diabetic coma with a past history of diabetes insipidus was diagnosed as having Klinefelter's syndrome by endocrinological examination and sex chromosome analysis. In this case, glucose tolerance test was normalized half a year later and blood glucose was well controlled with diet therapy alone.
(Internal Medicine 31 : 917-921, 1992)

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