Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Hemolytic Uremic Syndrome Associated with Immunoglobulin A Nephropathy: A Case Report and Review of Cases of Hemolytic Uremic Syndrome with Glomerular Disease
Sumiharu MORITA, Toshiyuki SAKAI, Naoko OKAMOTO, Ayumi FUNABIKI, Yumi OKADA, Yutaka HASEGAWA, Kazuhiko AMANO, Norishige YOSHIKAWA, Masato KASUGA
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Keywords: nephrotic syndrome, hemolytic anemia, thrombocytopenia
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1999 Volume 38 Issue 6 Pages 495-499

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Abstract

A 35-year-old man with immunoglobulin A (IgA) nephropathy who developed hemolytic uremic syndrome (HUS) presented with transient elevation of serum creatinine, thrombocytopenia, and hemolytic anemia with fragmented red cells with nephrotic syndrome. Hemolytic anemia and the temporarily deteriorated renal function were improved after hemodialysis and plasma exchange. Histological findings were consistent with HUS and IgA nephropathy. Including this case, we reviewed the cases of HUS accompanied by glomerular diseases reported from 1969 to 1996. Surprisingly, most cases showed nephrotic syndrome at the onset of HUS. Several possible relationships between HUS and nephrotic syndrome are discussed.
(Internal Medicine 38: 495-499, 1999)

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