The authors have presented the experiences which they had when they tried Ananase in the otorhinological field. In the distended cheek occurred after the operation to totally eliminate sinusitis, Ananase was effective in all 8 patients. In 27 patients in whom Ananase was given as the non-operational treatment of chronic sinusitis, it was significantly effective in 8, effective in 11 but not effective in 8 patients. In 19 ears with tubal obstruction or exudative otitis media in 15 patients, Ananase was significantly effective in 11, effective in 4 but not effective in 4 ears. It can be expected that Ananase is effective in various types of otorhinolaryngological disorders, but with its easiness of use.