The cross-coupling reaction of the Grignard reagent with alkylating reactants (RBr, RI, and ROTs)was carried out in the presence of copper (II) acetate and organic copper (II) complex catalysts (0.01- 0.05 molar amount) in tetrahydrofuran. The reaction readily gave higher hydrocarbons (n-C₁₇H₃₆, n-C₂₃H₄₈, n -C₂₆H₅₄, n -C₂₇H₅₆, n -C₂₉H₆₀, n -C₃₀H₆₂, and n-C₃₁H₆₄ ), 1 - phenyloctadecane, and 1-cyclohexyloctadecane as the desired products in 90 99% isolated yields under mild conditons (-10-60° C, 2 -5h). In particular, copper (II) acetate was found to be much more effective than con ventional inorganic copper (II) salt catalysts (Li₂CuCl₄, CuX₂) from the viewpoints of availability, solubility, stability, and activity.847

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