To analyze the frequency of methicillin resistant staphylococcus aureus (MRSA) infection, we investigated the cases who were infected with MRSA in our hospital. From 1989 to 1993, 9906 cases of hospitalized patients were available for investigation. Of these 8372 cases required surgical treatment. There were 31 cases whose wounds were infected. Of these 10 cases were identified as having MRSA infection. Wound infection with MRSA increased in association with the increase in usage of third generation cephem antibiotics after surgical treatment. Another 10 cases, aged from 62 to 92 years (average 78.4 years), contracted MRSA infections, although they had not had not any surgical treatment although all of these patients were compromised hosts. The mortality rate of MRSA pneumonia was 33.3%. For prevention of nosocomial MRSA infection, systemic organization of an MRSA infection team is very important.
