Subarachnoid Dissemination of Pineal Germinoma 9 Years After Radiation Therapy without Local Relapse —Case Report—

Kazuhiko TOKORO; Yasuhiro CHIBA; Shizuo MURASE; Saburo YAGISHITA; Yoshikazu KYUMA

doi:10.2176/nmc.31.725

Subarachnoid Dissemination of Pineal Germinoma 9 Years After Radiation Therapy without Local Relapse

—Case Report—

Kazuhiko TOKORO, Yasuhiro CHIBA, Shizuo MURASE, Saburo YAGISHITA, Yoshikazu KYUMA

Author information

Keywords: germinoma, subarachnoid dissemination, spinal metastasis, pineal region, radiation therapy

JOURNAL FREE ACCESS

1991 Volume 31 Issue 11 Pages 725-728

DOI https://doi.org/10.2176/nmc.31.725

Details

Abstract

A 22-year-old female developed intracranial and spinal subarachnoid metastases 9 years after radiation therapy for a pineal germinoma. Computed tomographic scans showed no evidence of local recurrence. Cerebrospinal axis irradiation achieved total remission. Delayed subarachnoid dissemination may be caused by germinoma cells remaining dormant in the subarachnoid space, outside the radiation field.

Corresponding author

Register with J-STAGE for free!