Experimental Investigation of a New Liquid Embolization Method: Enhancing Effect of 25% Ethanol on Conjugated Estrogen

Takayuki SUGAWARA; Akira TAKAHASHI; Ching Chan SU; Toshihiro SUGA; Takashi YOSHIMOTO; Jiro SUZUKI

doi:10.2176/nmc.32.59

Takayuki SUGAWARA, Akira TAKAHASHI, Ching Chan SU, Toshihiro SUGA, Takashi YOSHIMOTO, Jiro SUZUKI

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Keywords: estrogen, ethanol, embolization, intravascular surgery

JOURNAL FREE ACCESS

1992 Volume 32 Issue 2 Pages 59-64

DOI https://doi.org/10.2176/nmc.32.59

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Abstract

A new liquid embolization material applicable to intracranial lesions was evaluated by selective renal artery embolization in mongrel dogs. Absolute and diluted ethanol, estrogen, and estrogen in 25% ethanol (ethanol-estrogen) were injected. The embolization and side effects were investigated angiographically and histologically. Ethanol-estrogen caused similar embolization to absolute ethanol, but no direct damage to perivascular tissue, and is considered a promising embolization agent in intravascular surgery.

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