Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Trousseau Syndrome with Nonbacterial Thrombotic Endocarditis in a Patient with Uterine Cancer
Saki Ito, Hiroyuki Yoshitomi, Misun Pak, Hiroshi Kawahara, Takeshi Oshima, Shimpei Ito, Nobuhide Watanabe, Hirotomo Sato, Tomoko Adachi, Masaki Takeda, Takashi Sugamori, Nobuyuki Takahashi, Akihiro Endo, Tomoka Ishibashi, Kazuaki Tanabe
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Keywords: aseptic vegetation, recurrent stroke, unfractionated heparin, cancer
JOURNAL OPEN ACCESS

2013 Volume 52 Issue 12 Pages 1353-1358

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Abstract

This paper aims to describe the usefulness of transthoracic echocardiography in the follow-up of recurrent nonbacterial thrombotic endocarditis (NBTE) associated with neoplastic conditions. A 60-year-old woman with advanced uterine cancer developed recurrent areas of aseptic vegetation on the mitral valve along with cerebral, renal and splenic embolisms. Echocardiographic assessments revealed vegetation and thrombotic events on three occasions. In this case, transthoracic echocardiography was effective in following the decreased frequency of attachment of the NBTE vegetation to the mitral valve and reductions in the size of the area of vegetation following treatment with unfractionated heparin infusion, hysterectomy and chemotherapy.

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© 2013 by The Japanese Society of Internal Medicine
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