Chinese Hypertriglycerideamic Subjects of Different Ages Responded Differently to Consuming Oil with Medium- and Long-Chain Fatty Acids

Changyong XUE; Yinghua LIU; Jin WANG; Zixin ZHENG; Yuehong ZHANG; Yong ZHANG; Rongxin ZHANG; Xiaoming YU; Hongjiang JIN; Naohisa NOSAKA; Chie ARAI; Michio KASAI; Toshiaki AOYAMA; Jian WU

doi:10.1271/bbb.80827

Food & Nutrition Science Regular Papers

Chinese Hypertriglycerideamic Subjects of Different Ages Responded Differently to Consuming Oil with Medium- and Long-Chain Fatty Acids

Changyong XUE, Yinghua LIU, Jin WANG, Zixin ZHENG, Yuehong ZHANG, Yong ZHANG, Rongxin ZHANG, Xiaoming YU, Hongjiang JIN, Naohisa NOSAKA, Chie ARAI, Michio KASAI, Toshiaki AOYAMA, Jian WU

Author information

Changyong XUE
Department of Nutrition, Chinese PLA General Hospital
Yinghua LIU
Department of Nutrition, Chinese PLA General Hospital
Jin WANG
Department of Nutrition, Chinese PLA General Hospital
Zixin ZHENG
Department of Nutrition, Chinese PLA General Hospital
Yuehong ZHANG
Department of Nutrition, Chinese PLA General Hospital
Yong ZHANG
Department of Nutrition, Chinese PLA General Hospital
Rongxin ZHANG
Department of Nutrition, Chinese PLA General Hospital
Xiaoming YU
Department of Nutrition, Chinese PLA General Hospital
Hongjiang JIN
Department of Nutrition, Chinese PLA General Hospital
Naohisa NOSAKA
Central Research Laboratory, Nisshin OilliO Group
Chie ARAI
Central Research Laboratory, Nisshin OilliO Group
Michio KASAI
Central Research Laboratory, Nisshin OilliO Group
Toshiaki AOYAMA
Central Research Laboratory, Nisshin OilliO Group
Jian WU
Central Research Laboratory, Nisshin OilliO Group
National Institute of Health and Nutrition

Keywords: medium- and long-chain triacylglycerols, blood triglyceride, body fat, hypertriglyceridemia, age

JOURNAL FREE ACCESS

2009 Volume 73 Issue 8 Pages 1711-1717

DOI https://doi.org/10.1271/bbb.80827

View "Advance Publication" version (August 7, 2009).

Details

Abstract

Two groups of Chinese hypertriacylglycerolemic subjects were recruited and randomized to medium- and long-chain triacylglycerols (MLCT) oil or long-chain triacylglycerols (LCT) oil. Two subgroups were divided by age at less or more 60 years in both groups. Both oils were consumed at 25–30 g daily for 8 weeks. Anthropometry, blood biochemicals, and computed tomography (CT) scanning were done at the initial and final times. In subjects of age less than 60 years on MLCT, the body weight, body mass index (BMI), waist circumference (WC), hip circumference (HC), waist-hip ratio (WHR), body fat, total fat area, and subcutaneous fat area were significantly lower than those of the initial values, and the change values in these indicators and visceral fat area lowered significantly as compared with those on LCT. The levels of apoB, apoA2, apoC2, and apoC3 decreased significantly, and the change in values in the levels of triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), apoA1, apoB, apoA2, apoC2, apoC3 were significantly lower on MLCT of age under 60 years as compared with those on LCT.

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