2007 Volume 71 Issue 4 Pages 546-549
Background In the clinical situation, the saddle-back (S-B) type is more frequently detected than the coved type. In the present study, the discrimination of Brugada syndrome from the S-B type individuals using a marker of the standard 12-lead electrocardiography (ECG) was attempted. Methods and Results The study group consisted of 55 individuals with the S-B type in whom pilsicainide provocation test (PLC test) was carried out. The time from the onset of the QRS wave in lead V2 (IV 2) to the peak of the late R-like wave in the QRS wave (PV2), and the time from IV2 to the offset of the QRS wave in lead V5 (EV5) were measured. The coved type was induced by the PLC test in 29 cases (N-C group), but not in the remaining 26 cases (N-N group). The (IV2 -PV2) - (IV2 - EV5) value before the PLS test was greater in the N-C group than in the N-N group. The negative predictive value of `(IV2 - PV2) - (IV2 - EV5) ≥0' was 76.4% for the prediction of a positive PLC test. Conclusions A `(IV2 - PV2) - (IV2 - EV5) ≥0' is a useful ECG marker for the discrimination of Brugada syndrome in the S-B type individuals. (Circ J 2007; 71: 546 - 549)