Circulation Journal
Online ISSN : 1347-4820
Print ISSN : 1346-9843
ISSN-L : 1346-9843
Reviews
Orthostatic Hypertension
A Measure of Blood Pressure Variation for Predicting Cardiovascular Risk
Kazuomi Kario
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2009 Volume 73 Issue 6 Pages 1002-1007

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Abstract

Orthostatic hypertension, a measure of blood pressure (BP) variability, is a clinically important pathologic condition associated with the progression of target organ damage and subsequent cardiovascular risk. Orthostatic hypertension precedes hypertension and could be considered as prehypertension if a patient has seated clinic BP <140/90 mmHg. The simple examination of orthostatic BP changes using a self-measured home BP monitoring, through which abnormal pathological conditions can be detected with high reproducibility without the white-coat effect. Orthostatic hypertension is associated with morning hypertension and increased neurohumoral activation; however, the precise mechanism of orthostatic hypertension remains unclear, and accumulation of further clinical evidence is necessary. (Circ J 2009; 73: 1002-1007)

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© 2009 THE JAPANESE CIRCULATION SOCIETY
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