2003 Volume 51 Issue 6 Pages 683-687
Four new cycloartane glycosides, named aquilegiosides C—F, were isolated from the dried aerial parts of Aquilegia vulgaris. Their structures were determined by two dimensional (2D) NMR spectroscopic analysis and chemical evidence. Aquilegiosides C—F suppressed the proliferation of lymphocytes in mouse allogeneic mixed lymphocyte reaction with IC50, ranging from 3.7×10−5 to 2.2×10−4 M.