Endocrine Journal
Online ISSN : 1348-4540
Print ISSN : 0918-8959
ISSN-L : 0918-8959
NOTES
Excess Urinary Iodine Is Associated with Autoimmune Subclinical Hypothyroidism among Egyptian Women
Ahmed ALSAYEDAdela M. GADHoda ABDEL-BASETAbeer ABDEL-FATTAHAdel AHMEDAdel AZAB
Author information
JOURNAL FREE ACCESS

2008 Volume 55 Issue 3 Pages 601-605

Details
Abstract

Excessive iodine exposure was reported to be associated with thyroid dysfunctions.The aim of this study is to evaluate the link between excess urinary iodine as the prime indicator of excessive iodine intake and autoimmune subclinical hypothyroidism (SCH) among Egyptian women. Seventy three women with autoimmune SCH and 60 age- matched healthy women as controls were enrolled in this study. TSH, FT4, urinary iodine concentrations (UIC) and thyroid peroxidase antibody (TPOAb) were estimated. The levels of urinary iodine were significantly higher in patients with SCH as compared with control subjects, (326.97 112.98 vs. 274.45 98.75 ug/l, p<0.01). In patients with SCH, there was a significant correlation between UIC and TSH levels. Also, a significant correlation between UIC and TPOAb was found. We conclude that excessive iodine intake may trigger thyroid autoimmunity and eventually thyroid hypofunction among Egyptian women.

Content from these authors
© The Japan Endocrine Society
Previous article Next article
feedback
Top