Desquamative Interstitial Pneumonia (DIP) in a Patient with Rheumatoid Arthritis: Is DIP Associated with Autoimmune Disorders?

Internal Medicine

Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918

CASE REPORTS

Desquamative Interstitial Pneumonia (DIP) in a Patient with Rheumatoid Arthritis: Is DIP Associated with Autoimmune Disorders?

Hiroshi Ishii, Atsuko Iwata, Noriho Sakamoto, Shunji Mizunoe, Hiroshi Mukae, Jun-ichi Kadota

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Keywords: autoimmune disorders, desquamative interstitial pneumonia, rheumatoid arthritis, smoking

JOURNAL OPEN ACCESS

2009 Volume 48 Issue 10 Pages 827-830

DOI https://doi.org/10.2169/internalmedicine.48.1876

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Abstract

Desquamative interstitial pneumonia (DIP) is a rare pattern of diffuse parenchymal lung disease known as one of the idiopathic interstitial pneumonias and is considered to be a smoking- or dust inhalation-related interstitial pneumonia in the majority of cases. This report presents the first case of DIP in which the pulmonary manifestation preceded the onset of rheumatoid arthritis. This case and our review of twenty-four DIP cases (nineteen cases previously-reported from Japan, plus five cases in our departments) indicate the possibility that the DIP pattern is an additional form of diffuse interstitial pneumonia that may develop in association with autoimmune diseases.

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© 2009 by The Japanese Society of Internal Medicine

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