Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Intravascular Large B-cell Lymphoma Presenting Pulmonary Arterial Hypertension as an Initial Manifestation
Takeshi Kotake, Satoru Kosugi, Takayuki Takimoto, Soichi Nakata, Junko Shiga, Yasuhiro Nagate, Tsutomu Nakagawa, Hironori Take, Shuichi Katagiri
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Keywords: intravascular large B-cell lymphoma (IVLBCL), pulmonary arterial hypertension (PAH), 18F-fluorodeoxyglucose positron emission tomography (FDG-PET)
JOURNAL OPEN ACCESS

2010 Volume 49 Issue 1 Pages 51-54

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Abstract

We report a 39-year-old man with intravascular large B-cell lymphoma (IVLBCL) who had been treated as a case with pulmonary arterial hypertension (PAH) for one year. After he became worse, diffuse pulmonary 18F-fluorodeoxyglucose (FDG) uptake in positron emission tomography (PET) suggested the existence of IVLBCL in the lung showing normal CT images. The diagnosis was confirmed with random transbronchial lung biopsy, and he was then successfully treated. Since IVLBCL presenting PAH has been rare and is difficult to diagnose, early application of FDG-PET may provide early recognition of the disorder, leading to a better outcome.

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© 2010 by The Japanese Society of Internal Medicine
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