Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Toxic Hepatitis Induced by Show-Wu-Pian, a Chinese Herbal Preparation
Maiko Furukawa, Saeko Kasajima, Yuri Nakamura, Meiko Shouzushima, Naho Nagatani, Akira Takinishi, Ayumi Taguchi, Mikiko Fujita, Akiko Niimi, Ryoichi Misaka, Hikaru Nagahara
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Keywords: toxic hepatitis, drug induced hepatitis, herbal medicine, Shou-Wu-Pian
JOURNAL OPEN ACCESS

2010 Volume 49 Issue 15 Pages 1537-1540

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Abstract

Herbal preparations are widely available and often regarded by the public as harmless remedies for a variety of medical ailments. However, some of these products or their metabolites can cause adverse effects such as liver damage. In this case report a 53-year-old female taking Shou-Wu-Pian for 8 months presented with acute hepatitis. Histopathological assessment of liver tissue obtained by biopsy was consistent with a toxic reaction. Clinical and biochemical resolution was brought about following cessation of the drug. It is important for clinicians to consider Chinese herbal preparations as a potential cause of abnormal liver function test results.

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© 2010 by The Japanese Society of Internal Medicine
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