The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
TRIENINE, AN ANTITUMOR TRIENE ANTIBIOTIC
ADORJAN ASZALOSROBERT S. ROBISONPAUL LEMANSKIBERNARD BERK
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1968 Volume 21 Issue 10 Pages 611-615

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Abstract

Trienine, a new antitumor antibiotic, was isolated from the fermentation broth of Streptomyces SC3725. The substance, which contains three conjugated double bonds in a molecule weighing approximately 1, 400, is active in vitro against gram-positive bacteria, as well as against several yeast and fungi. Trienine is also active as an inhibitor of the growth of the 5 WM tumor.

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© Japan Antibiotics Research Association
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