The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
ISOLATION AND STRUCTURE OF ASCOFURANONE AND ASCOFRANOL, ANTIBIOTICS WITH HYPOLIPIDEMIC ACTIVITY
HIROSHI SASAKITOMOYOSHI HOSOKAWAMIKIO SAWADAKUNIO ANDO
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1973 Volume 26 Issue 11 Pages 676-680

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Abstract

A new antibiotic with hypolipidemic activity, ascofuranone, C23H29C1O5, and related substance, ascofuranol, C23H31C1O5, were isolated from the filter cake of the fermented broth of Ascochyta viciae LIBERT, an ascochlorin-producing fungus, and their structures were elucidated. They possess 3-substituted-5-chloro-orcylaldehyde moiety with novel sesquiterpenyl side chains.

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© Japan Antibiotics Research Association
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