The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
A NEW ANTIBIOTIC XK-62-2 (SAGAMICIN)
I. ISOLATION, PHYSICOCHEMICAL AND ANTIBACTERIAL PROPERTIES
RYO OKACHIISAO KAWAMOTOSEIGO TAKASAWAMITSUYOSHI YAMAMOTOSEIJI SATOTOMOYASU SATOTAKASHI NARA
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1974 Volume 27 Issue 10 Pages 793-800

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Abstract

A new aminoglycoside antibiotic XK-62-2 (Sagamicin) produced by Micromonospora sagamiensis var. nonreducans nov. sp. MK 62 was isolated from its fermentation beer by use of a cationic exchange resin and silica-gel column chromatography. The purified antibiotic showed a close similarity to gentamicin C complex in physical, chemical, and antimicrobial properties, but a significant difference from gentamicin in its more remarkable activity against some Pseudomonas aeruginosa strains resistant to gentamicin C1a.

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© Japan Antibiotics Research Association
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