STUDIES ON ACULEACIN. II ISOLATION AND CHARACTERIZATION OF ACULEACINS B, C, D, E, F and G

SHUZO SATOI; AKIRA YAGI; KATSUMI ASANO; KIMIO MIZUNO; TETSUO WATANABE

doi:10.7164/antibiotics.30.303

The Journal of Antibiotics

Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820

STUDIES ON ACULEACIN. II

ISOLATION AND CHARACTERIZATION OF ACULEACINS B, C, D, E, F and G

SHUZO SATOI, AKIRA YAGI, KATSUMI ASANO, KIMIO MIZUNO, TETSUO WATANABE

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1977 Volume 30 Issue 4 Pages 303-307

DOI https://doi.org/10.7164/antibiotics.30.303

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Abstract

Six new antibiotics were isolated as the minor components related to aculeacin A from the culture broth of Aspergillus aculeatus M-4214 and named as aculeacins B, C, D, E, F and G. Their physico-chemical properties were analogous to those of aculeacin A and they showed significant activity against fungi. All of the minor components liberated palmitic acid on alkaline hydrolysis. Amino acid analysis showed that threonine and hydroxyproline are common constituents of aculeacins.

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