BACILLOMYCIN F, A NEW ANTIBIOTIC OF ITURIN GROUP: ISOLATION AND CHARACTERIZATION

AÌCHA MHAMMEDI; FRANCOISE PEYPOUX; FRANCOISE BESSON; GEORGES MICHEL

doi:10.7164/antibiotics.35.306

The Journal of Antibiotics

Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820

BACILLOMYCIN F, A NEW ANTIBIOTIC OF ITURIN GROUP: ISOLATION AND CHARACTERIZATION

AÌCHA MHAMMEDI, FRANCOISE PEYPOUX, FRANCOISE BESSON, GEORGES MICHEL

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JOURNAL FREE ACCESS

1982 Volume 35 Issue 3 Pages 306-311

DOI https://doi.org/10.7164/antibiotics.35.306

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Abstract

Bacillomycin F, a new family of iturin group antibiotics, was isolated from Bacillus subtilis. It shows a potent antifungal activity and a narrow spectrum against bacteria. Acid hydrolysis gave a peptide moiety which contains 7 mole of amino acids: D-Asp₂, L-Glu₁, L-Thr₁, L-Pro₁, D-Tyr₁ and a lipid moiety which is a mixture of two main long chain n-amino acids: β-amino-14-methylpentadecanoic acid (58%) and 3-amino-14-methylhexadecanoic acid (23%).

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