1983 Volume 36 Issue 10 Pages 1263-1267
Pyrrolomycins C, D and E, new members of pyrrolomycins produced by Actinosporangium vitaminophilium SF-2080, have been isolated by chromatography on a basic alumina column. Three antibiotics have chlorinated pyrrole nuclei linked directly or via carbonyl function to the dichlorophenol moiety. Pyrrolomycins C and E are active against Gram-positive bacteria, while the spectrum of pyrrolomycin D is broad including Gram-positive, Gram-negative bacteria and fungi.