SAFRACINS, NEW ANTITUMOR ANTIBIOTICS I. PRODUCING ORGANISM, FERMENTATION AND ISOLATION

YOSHIFUMI IKEDA; HARUMI IDEMOTO; FUMIHIRO HIRAYAMA; KATSUHIRO YAMAMOTO; KAZUHIRO IWAO; TOSHIMI ASAO; TOMOHIKO MUNAKATA

doi:10.7164/antibiotics.36.1279

SAFRACINS, NEW ANTITUMOR ANTIBIOTICS

I. PRODUCING ORGANISM, FERMENTATION AND ISOLATION

YOSHIFUMI IKEDA, HARUMI IDEMOTO, FUMIHIRO HIRAYAMA, KATSUHIRO YAMAMOTO, KAZUHIRO IWAO, TOSHIMI ASAO, TOMOHIKO MUNAKATA

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JOURNAL FREE ACCESS

1983 Volume 36 Issue 10 Pages 1279-1283

DOI https://doi.org/10.7164/antibiotics.36.1279

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Abstract

Safracins, new antibiotics with a novel skeleton, were discovered in a culture broth of Pseudomonas sp. The producing organism has been identified as Pseudomonas fluorescens. Safracins A and B were isolated by ethyl acetate extraction and chromatography on silica gel.

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