THE AURACHINS, NEW QUINOLINE ANTIBIOTICS FROM MYXOBACTERIA: PRODUCTION, PHYSICO-CHEMICAL AND BIOLOGICAL PROPERTIES
1987 Volume 40 Issue 3 Pages 258-265
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1987 Volume 40 Issue 3 Pages 258-265
The aurachins, new quinoline alkaloids, were extracted with acetone from the biomass of the myxobacterium, Stigmatella aurantiaca strain Sg a!5 and purified by column chromatography. The four described aurachins A, B, C and D, were inhibitory for Gram-positive bacteria and a few yeasts and molds. They blocked NADH oxidation in beef heart submitochondrial particles.
