DEOXYMULUNDOCANDIN -A NEW ECHINOCANDIN TYPE ANTIFUNGAL ANTIBIOTIC

TRIPTIKUMAR MUKHOPADHYAY; KIRITY ROY; R. G. BHAT; S. N. SAWANT; J. BLUMBACH; B. N. GANGULI; H. W. FEHLHABER; H. KOGLER

doi:10.7164/antibiotics.45.618

TRIPTIKUMAR MUKHOPADHYAY, KIRITY ROY, R. G. BHAT, S. N. SAWANT, J. BLUMBACH, B. N. GANGULI, H. W. FEHLHABER, H. KOGLER

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JOURNAL FREE ACCESS

1992 Volume 45 Issue 5 Pages 618-623

DOI https://doi.org/10.7164/antibiotics.45.618

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Abstract

A new echinocandin type antifungal antibiotic, deoxymulundocandin, C₄₈H₇₇N₇O₁₅, was isolated from the culture filtrate and mycelia of a fungal culture, Aspergillus sydowii (Bainier and Sartory) Thorn and Church var. nov. mulundensis Roy (Culture No. Y-30462). The structure was established by comparative GC-MS analyses of the derivatized acid hydrolysates of deoxymulundocandin and mulundocandin as well as by the high field NMR experiments (COSY, NOESY and DEPT).

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