BIOSYNTHETIC CAPACITIES OF ACTINOMYCETES. 2# JUGLOMYCIN Z, A NEW NAPHTHOQUINONE ANTIBIOTIC FROM Streptomyces tendae

HANS-PETER FIEDLER; ANDREAS KULIK; TRAUGOTT C. SCHÜZ; CORINNA VOLKMANN; AXEL ZEECK

doi:10.7164/antibiotics.47.1116

BIOSYNTHETIC CAPACITIES OF ACTINOMYCETES. 2# JUGLOMYCIN Z, A NEW NAPHTHOQUINONE ANTIBIOTIC FROM Streptomyces tendae

HANS-PETER FIEDLER, ANDREAS KULIK, TRAUGOTT C. SCHÜZ, CORINNA VOLKMANN, AXEL ZEECK

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JOURNAL FREE ACCESS

1994 Volume 47 Issue 10 Pages 1116-1122

DOI https://doi.org/10.7164/antibiotics.47.1116

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Abstract

A new juglomycin-type antibiotic was identified by a HPLC-diode array screening technique in the culture filtrate of Streptomyces tendae Tü 901/8c. Juglomycin Z (1) differs from all other known juglomycin compounds by an additional methyl group in position 3 of the naphthoquinone ring system. Juglomycin Z is antibiotically active against Gram-positive and Gram-negative bacteria and against yeasts.

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