Melanocins A, B and C, New Melanin Synthesis Inhibitors Produced by Eupenicillium shearii II. Physico-chemical Properties and Structure Elucidation

JONG-PYUNG KIM; BYOUNG-KWON KIM; BONG-SIK YUN; IN-JA RYOO; IN-KYOUNG LEE; WON-GON KIM; YU-RYANG PYUN; ICK-DONG YOO

doi:10.7164/antibiotics.56.1000

Melanocins A, B and C, New Melanin Synthesis Inhibitors Produced by Eupenicillium shearii

II. Physico-chemical Properties and Structure Elucidation

JONG-PYUNG KIM, BYOUNG-KWON KIM, BONG-SIK YUN, IN-JA RYOO, IN-KYOUNG LEE, WON-GON KIM, YU-RYANG PYUN, ICK-DONG YOO

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JOURNAL FREE ACCESS

2003 Volume 56 Issue 12 Pages 1000-1003

DOI https://doi.org/10.7164/antibiotics.56.1000

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Abstract

New melanin synthesis inhibitors, melanocins A, B and C, were isolated from the fermentation broth and extract of mycelium of Eupenicillium shearii F80695. The structures of melanocins were established by spectroscopic methods. They are formamide compounds. In particular, melanocin A has an isocyanide group.

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