The Journal of Biochemistry
Online ISSN : 1756-2651
Print ISSN : 0021-924X
5-Phosphomevalonic Acid as the Intermediate of the Enzymatic Synthesis of Bacterial Phytoene
SHIRO OHNOKIGINZABURO SUZUESHOZO TANAKA
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1962 Volume 52 Issue 6 Pages 423-427

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Abstract

1. The formation of phosphorylated derivatives of mevalonic acid in the presence of adenosine triphosphate and Mn++ by enzymes extracted from Staphylococcus is described.
2. One of the products was purified by various chromatographic procedures and shown to be identical with 5-phosphomeva-lonic acid.
3. 5-Phosphomevalonic acid was shown to be converted to phytoene with twice the efficiency of the DL-mevalonic acid.

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© The Japanese Biochemical Society
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