Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Occurrence of Paroxysmal Synchronous EEG Discharges in Subcortical Arteriosclerotic Encephalopathy (Binswanger's Disease)
Yasuo KURODAAkio IKEDAKazuhiro KUROHRARyusuke KAKIGISeiji RYUHHiromu KOUDANoriyuki MISAGOHajime SUGIHARA
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1993 Volume 32 Issue 3 Pages 243-246

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Abstract

A 72-year-old patient with von Recklinghausen's disease showed akinetic mutism within 6 months of the onset of dementia. The findings of diffuse cerebral atrophy on CT and periodic synchronous discharges (PSDs) in EEG suggested Creutzfeldt-Jakob disease. However, autopsy findings of diffuse softening of the subcortical white matter and marked arteriosclerotic changes of the subcortical arterioles with sparing of the cortex in the cerebrum confirmed a diagnosis of Binswanger's disease. Binswanger's disease should be included in the differential diagnosis of dementia showing PSDs in EEG.
(Internal Medicine 32: 243-246, 1993)

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© The Japanese Society of Internal Medicine
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